Contact Dermatitis  
Histopathology of Acute Contact Dermatitis

Histopathology of Acute Contact Dermatitis

Description : Acute contact dermatitis is characterized histologically by the presence of intraepidermally located vesicles which, in the early stages, may be infiltrated by mononuclear cells. After a few days the inflammatory cell infiltrate will also include neutrophils.

Intercellular edema (spongiosis) and intracellular edema are often present in the epidermis adjacent to the vesicles.

Acute contact dermatitis is characterized by the presence of intra epidermally located vesicles, which in the early stage may be infiltrated 39 x .

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