Metabolic Disorders  
Histopathology of Primary Cutaneous Amyloid

Histopathology of Primary Cutaneous Amyloid

Description : In a section stained with hematoxylin and eosin, thamyloid appears as granular, faintly eosinophilic aggregates that frequently contain clefts, as the result of shrinkage of the amyloid during the process of fixation and dehydration. A chronic inflammatory infiltrate containing large numbers of plasma cells is often present at the periphery of the mass of amyloid.

In this biopsy from the patient with the postauricular cutaneous amyloid, the deposits of amyloid can be seen as eosinophilic granular aggregates. H&E 560x.

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