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 Metabolic Disorders  
Histopathology of Gouty Tophi

Histopathology of Gouty Tophi

Description : The histologic sections reveal either uric acid crystals or their remnants, surrounded by foreign body- giant cells and changes of chronic inflammation.

For the histologic examination of tophi, the tissue. should be fixed in alcohol, since urate crystals are water soluble and aqueous formalin solution will dissolve the needle-shaped crystals.

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